Usually means: Adjust slightly to improve performance.
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We found 42 dictionaries that define the word tweak:

General (27 matching dictionaries)
  1. tweak: Longman Dictionary of Contemporary English
  2. tweak: Merriam-Webster
  3. tweak: Oxford Learner's Dictionaries
  4. tweak: American Heritage Dictionary of the English Language
  5. tweak: Collins English Dictionary
  6. tweak: Vocabulary.com
  7. Tweak, tweak: Wordnik
  8. tweak: Cambridge Advanced Learner's Dictionary
  9. tweak: Wiktionary
  10. tweak: Webster's New World College Dictionary, 4th Ed.
  11. tweak: The Wordsmyth English Dictionary-Thesaurus
  12. tweak: Infoplease Dictionary
  13. tweak: Dictionary.com
  14. tweak (v.): Online Etymology Dictionary
  15. tweak: Cambridge Essential American English Dictionary
  16. Tweak (band), Tweak (company), Tweak (programming environment), Tweak: Wikipedia, the Free Encyclopedia
  17. Tweak: Online Plain Text English Dictionary
  18. tweak: Webster's Revised Unabridged, 1913 Edition
  19. tweak: Rhymezone
  20. tweak: AllWords.com Multi-Lingual Dictionary
  21. tweak: Webster's 1828 Dictionary
  22. tweak: FreeDictionary.org
  23. tweak: Mnemonic Dictionary
  24. Tweak: The Word Detective
  25. tweak: TheFreeDictionary.com

Business (1 matching dictionary)
  1. tweak: Legal dictionary

Computing (6 matching dictionaries)
  1. tweak: Free On-line Dictionary of Computing
  2. tweak: Netlingo
  3. tweak: Computer Telephony & Electronics Dictionary and Glossary
  4. Tweak: Tech Terms Computer Dictionary
  5. Webopedia (No longer online)
  6. tweak: Encyclopedia

Medicine (2 matching dictionaries)
  1. online medical dictionary (No longer online)
  2. tweak: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. tweak: Idioms

Science (1 matching dictionary)
  1. TWEAK: Cytokines & Cells Online Pathfinder Encyclopaedia

Slang (1 matching dictionary)
  1. tweak, tweak, tweak, tweak, tweak, tweak: Green’s Dictionary of Slang

Sports (2 matching dictionaries)
  1. Mountain Bike Slang (No longer online)
  2. Hickok Sports Glossaries (No longer online)

Tech (1 matching dictionary)
  1. AUTOMOTIVE TERMS (No longer online)

(Note: See tweaked as well.)

Definitions from Wiktionary (
)
American English Definition British English Definition
verb:  (transitive) To pinch and pull with a sudden jerk and twist; to twitch.
verb:  (transitive, informal) To adjust slightly; to fine-tune.
verb:  (transitive) To tease, to annoy; to get under the skin of (someone, typically so as to irritate them, or by extension to enamor, frighten, etc).
verb:  (intransitive, US, slang) To abuse methamphetamines, especially crystal meth.
verb:  (intransitive, US, slang) To exhibit extreme nervousness, evasiveness when confronted by authorities, compulsiveness, erratic motion, excitability, etc, due to or mimicking the symptoms of methamphetamine abuse.
verb:  (intransitive, slang, by extension) To be extremely confused; to have no clue what is happening.
verb:  (military, weaponry, uncommon) From a catapult, to strike a target with a missile.
noun:  A sharp pinch or jerk; a twist or twitch.
noun:  A slight adjustment or modification.
noun:  Trouble; distress; tweag.
noun:  (obsolete, slang) A prostitute.
noun:  (slang) Methamphetamine.
noun:  (slang) A single inhalation of cocaine.
noun:  (cryptography) An additional input to a block cipher, used in conjunction with the key to select the permutation computed by the cipher.

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