Usually means: Behavior harmful to oneself intentionally.
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We found 25 dictionaries that define the word self-destructive:

General (24 matching dictionaries)
  1. self-destructive: Merriam-Webster
  2. self-destructive: Oxford Learner's Dictionaries
  3. self-destructive: American Heritage Dictionary of the English Language
  4. self-destructive, self-destructive: Collins English Dictionary
  5. self-destructive: Vocabulary.com
  6. Self-Destructive, self-destructive: Wordnik
  7. self-destructive: Cambridge Advanced Learner's Dictionary
  8. self-destructive: Wiktionary
  9. self-destructive: Webster's New World College Dictionary, 4th Ed.
  10. self-destructive: The Wordsmyth English Dictionary-Thesaurus
  11. self-destructive: Infoplease Dictionary
  12. self-destructive: Dictionary.com
  13. self-destructive: Cambridge Essential American English Dictionary
  14. Self-destructive: Wikipedia, the Free Encyclopedia
  15. Self-destructive: Online Plain Text English Dictionary
  16. self-destructive: Webster's Revised Unabridged, 1913 Edition
  17. self-destructive: Rhymezone
  18. Self-destructive: AllWords.com Multi-Lingual Dictionary
  19. self-destructive: Webster's 1828 Dictionary
  20. self-destructive: FreeDictionary.org
  21. self-destructive: Mnemonic Dictionary
  22. self-destructive: TheFreeDictionary.com

Medicine (1 matching dictionary)
  1. self-destructive: Merriam-Webster Medical Dictionary

(Note: See self-destructiveness as well.)

Definitions from Wiktionary (
)
American English Definition British English Definition
adjective:  Causing injury to oneself or harm to one's interests.

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