Usually means: Person with severe mental disorder.
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We found 34 dictionaries that define the word psycho:

General (25 matching dictionaries)
  1. psycho, psycho-: Merriam-Webster.com
  2. psycho, psycho-: Oxford Learner's Dictionaries
  3. psycho, psycho-: American Heritage Dictionary of the English Language
  4. psycho, psycho-: Collins English Dictionary
  5. psycho: Vocabulary.com
  6. Psycho, psycho, psycho-: Wordnik
  7. psycho, psycho-: Cambridge Advanced Learner's Dictionary
  8. psycho, psycho-: Wiktionary
  9. psycho, psycho (psych-): The Wordsmyth English Dictionary-Thesaurus
  10. psycho: Infoplease Dictionary
  11. Psycho-, psycho, psycho-: Dictionary.com
  12. psycho, psycho-: Online Etymology Dictionary
  13. psycho: Cambridge Essential American English Dictionary
  14. Psycho (Amy Shark song), Psycho (Hitchcock film), Psycho (Imelda May song), Psycho (Muse song), Psycho (Post Malone song), Psycho (Puddle of Mudd song), Psycho (Red Velvet song), Psycho (automaton), Psycho (disambiguation), Psycho (film), Psycho (film series), Psycho (franchise), Psycho (novel), Psycho (song), Psycho (soundtrack), Psycho (wrestler), Psycho: Wikipedia, the Free Encyclopedia
  15. Psycho-: Online Plain Text English Dictionary
  16. psycho-: Webster's Revised Unabridged, 1913 Edition
  17. psycho: Rhymezone
  18. Psycho-: AllWords.com Multi-Lingual Dictionary
  19. psycho, psycho-: MyWord.info
  20. psycho, psycho-: Free Dictionary
  21. psycho: Mnemonic Dictionary
  22. psycho, psycho, psycho-: Dictionary/thesaurus
  23. psycho, psycho-: Webster's New World College Dictionary, 4th Ed.

Art (1 matching dictionary)
  1. psycho-: A Cross Reference of Latin and Greek Elements

Business (1 matching dictionary)
  1. MoneyGlossary.com (No longer online)

Computing (1 matching dictionary)
  1. Psycho (disambiguation), Psycho: Encyclopedia

Medicine (2 matching dictionaries)
  1. online medical dictionary (No longer online)
  2. Psycho (disambiguation), psycho, psycho-: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. PSYCHO: Acronym Finder

Slang (3 matching dictionaries)
  1. psycho, psycho, psycho: Green’s Dictionary of Slang
  2. psycho: ESL Slang page
  3. Psycho, The Psycho, psycho-: Urban Dictionary

(Note: See psychos as well.)

Definitions from Wiktionary (
)
American English Definition British English Definition
adjective:  (colloquial or derogatory) Psychotic, psychopathic, or (broadly) otherwise insane.
noun:  (chiefly derogatory, slang) A person who is psychotic, psychopathic, or (broadly) otherwise insane.
noun:  (chiefly derogatory, slang, loosely) A person who acts in a bizarre or dangerous manner.
noun:  (informal) A class, at a college or university, in which psychology is taught.

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