Sorry, no online dictionaries contain the exact phrase opposite of profane.
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Reverse dictionary results:
1. sacred
2. holy
3. reverent
4. blessed
5. devote
6. reverence
7. sacrifice
8. sainthood
9. ven
10. venerant
11. veneration
12. venerative
13. worship
14. anointed
15. anointment
16. ceremony
17. dedicate
18. devoted
19. devotement
20. devotion
21. ex-voto
22. hallow'd
23. hallowedness
24. oblation
25. worshipping
26. adoration
27. anoint
28. ceremonial
29. clerically
30. consecration
31. dedicant
32. hode
33. oblate
34. offering
35. ovation
36. votive
37. anointer
38. clerkly
39. concelebration
40. consecrate

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You can look up the words in the phrase individually using these links:   opposite ?   of ?   profane ?
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