Usually means: Hybrid offspring of donkey, horse.
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We found 49 dictionaries that define the word mule:

General (26 matching dictionaries)
  1. mule: Merriam-Webster.com
  2. mule, mule: Oxford Learner's Dictionaries
  3. mule, mule: American Heritage Dictionary of the English Language
  4. mule: Collins English Dictionary
  5. mule: Vocabulary.com
  6. Mule, mule: Wordnik
  7. mule: Cambridge Advanced Learner's Dictionary
  8. Mule, mule: Wiktionary
  9. mule: Webster's New World College Dictionary, 4th Ed.
  10. mule: The Wordsmyth English Dictionary-Thesaurus
  11. mule: Infoplease Dictionary
  12. mule: Dictionary.com
  13. mule (1), mule (2): Online Etymology Dictionary
  14. mule: Cambridge Essential American English Dictionary
  15. M.U.L.E, MULE (video game), MULE, Mule (Foundation), Mule (band), Mule (bird), Mule (coin), Mule (dance), Mule (disambiguation), Mule (footwear), Mule (sheep), Mule (shoe), Mule (smuggling), Mule (software), Mule (surname), Mule, The Mule (song), The Mule: Wikipedia, the Free Encyclopedia
  16. Mule: Online Plain Text English Dictionary
  17. mule: Webster's Revised Unabridged, 1913 Edition
  18. mule: Rhymezone
  19. mule, mule (f): AllWords.com Multi-Lingual Dictionary
  20. mule: Webster's 1828 Dictionary
  21. Mule: Dictionary of Phrase and Fable (1898)
  22. mule: Free Dictionary
  23. mule: Mnemonic Dictionary
  24. mule: Dictionary/thesaurus

Art (2 matching dictionaries)
  1. Mule: Numismatic Dictionary
  2. Natural Magick (No longer online)

Computing (2 matching dictionaries)
  1. Mule: Free On-line Dictionary of Computing
  2. Mule (emacs), Mule (manufacturing), Mule (zoology), mule: Encyclopedia

Medicine (4 matching dictionaries)
  1. Mule: MedTerms.com Medical Dictionary
  2. online medical dictionary (No longer online)
  3. Mule (emacs), Mule (smuggling), Mule (zoology), mule: Medical dictionary
  4. Mule: Drug Medical Dictionary

Miscellaneous (5 matching dictionaries)
  1. Brilliant Dream Dictionary (No longer online)
  2. MULE: Acronym Finder
  3. AbbreviationZ (No longer online)
  4. mule: Idioms
  5. mule: Wordcraft Dictionary

Religion (2 matching dictionaries)
  1. Mule: Easton Bible
  2. Mule: Smith's Bible Dictionary

Science (1 matching dictionary)
  1. Bird On! (No longer online)

Slang (4 matching dictionaries)
  1. Mule (offensive): Racial Slur Database
  2. mule, mule: Green’s Dictionary of Slang
  3. Mule: Street Terms: Drugs and the Drug Trade
  4. The Mule: Urban Dictionary

Tech (3 matching dictionaries)
  1. AUTOMOTIVE TERMS (No longer online)
  2. DOD Dictionary of Military Terms: Joint Acronyms and Abbreviations (No longer online)
  3. Farrier & Hoofcare (No longer online)

(Note: See muleing as well.)

Definitions from Wiktionary (
)
American English Definition British English Definition
noun:  The generally sterile male or female hybrid offspring of a male donkey and a female horse.
noun:  The generally sterile hybrid offspring of any two species of animals.
noun:  (now rare) A hybrid plant.
noun:  (informal) A stubborn person.
noun:  (slang) A person paid to smuggle drugs.
noun:  (numismatics) A coin or medal minted with obverse and reverse designs not normally seen on the same piece, either intentionally or in error.
noun:  (roleplaying games) A MMORPG character, or NPC companion in a tabletop RPG, used mainly to store extra inventory for the owner's primary character.
noun:  Any of a group of cocktails involving ginger ale or ginger beer, citrus juice, and various liquors.
noun:  (sailing) A kind of triangular sail for a yacht.
noun:  A kind of cotton-spinning machine.
verb:  (transitive, slang) To smuggle (illegal drugs).
noun:  Any shoe with an upper covering the front of the foot but without a back flap or strap, leaving the heel exposed.
noun:  A surname.

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