tired, satiate, wearied, overjaded, sick, sick and tired, blasé, exhaustipated, mind-numbing, bored out of one's brains, more...

fresh, new, novel

over it, bored, unimpressed, weary, skeptical, more...

not naive,   bored with routine,   tired of everything,   tired bored,   losing innocence,   seen too much,   to be made cynical,   innocence lost,   seen enough,   loss of wonder