Usually means: Responsible for making decisions, leading.
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We found 16 dictionaries that define the word in charge:

General (11 matching dictionaries)
  1. in charge: Merriam-Webster
  2. in charge: Oxford Learner's Dictionaries
  3. in charge: Collins English Dictionary
  4. In-charge, in-charge: Wordnik
  5. in charge: Cambridge Advanced Learner's Dictionary
  6. in charge: Wiktionary
  7. in charge: Dictionary.com
  8. in charge: Rhymezone
  9. in charge: TheFreeDictionary.com

Business (2 matching dictionaries)
  1. in charge: Merriam-Webster Legal Dictionary
  2. in charge: Legal dictionary

Medicine (1 matching dictionary)
  1. in charge: Merriam-Webster Medical Dictionary

Miscellaneous (1 matching dictionary)
  1. in charge: Idioms

Slang (1 matching dictionary)
  1. in charge: Urban Dictionary

Definitions from Wiktionary (in charge)

adjective:  Having the responsibility of leading or overseeing.
adjective:  Having the power of command or control.
adjective:  (dated) In the care, custody or command (of someone).

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