Usually means: Significant interruption to normal flow.
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We found 33 dictionaries that define the word disruption:

General (23 matching dictionaries)
  1. disruption: Merriam-Webster.com
  2. disruption: Oxford Learner's Dictionaries
  3. disruption: Collins English Dictionary
  4. disruption: Vocabulary.com
  5. Disruption, disruption: Wordnik
  6. disruption: Cambridge Advanced Learner's Dictionary
  7. disruption: Wiktionary
  8. disruption: The Wordsmyth English Dictionary-Thesaurus
  9. disruption: Infoplease Dictionary
  10. disruption: Dictionary.com
  11. disruption: Online Etymology Dictionary
  12. disruption: Cambridge Essential American English Dictionary
  13. Disruption (adoption), Disruption: Wikipedia, the Free Encyclopedia
  14. Disruption: Online Plain Text English Dictionary
  15. disruption: Webster's Revised Unabridged, 1913 Edition
  16. disruption: Rhymezone
  17. disruption: AllWords.com Multi-Lingual Dictionary
  18. disruption: Webster's 1828 Dictionary
  19. disruption: Free Dictionary
  20. disruption: Mnemonic Dictionary
  21. disruption: Dictionary/thesaurus

Business (3 matching dictionaries)
  1. MoneyGlossary.com (No longer online)
  2. disruption: Legal dictionary
  3. BusinessDictionary.com (No longer online)

Computing (1 matching dictionary)
  1. disruption: Encyclopedia

Medicine (4 matching dictionaries)
  1. Dorland's Illustrated Medical Dictionary (No longer online)
  2. Reactive Attachment Disorder (No longer online)
  3. online medical dictionary (No longer online)
  4. Disruption: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. A Brief Critical Dictionary of Education (No longer online)

Slang (1 matching dictionary)
  1. Disruption: Urban Dictionary

(Note: See disrupt as well.)

Definitions from Wiktionary (
)
American English Definition British English Definition
noun:  An interruption to the regular flow or sequence of something.
noun:  A continuing act of disorder.
noun:  A breaking or bursting apart; a breach.

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    red,     orange,     neon green,     electric blue,     black, more...



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