Usually means: Make worse or more severe.
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We found 21 dictionaries that define the word acerbate:

General (19 matching dictionaries)
  1. acerbate: Merriam-Webster.com
  2. acerbate: American Heritage Dictionary of the English Language
  3. acerbate: Collins English Dictionary
  4. acerbate: Vocabulary.com
  5. acerbate: Wordnik
  6. acerbate: Wiktionary
  7. acerbate: Webster's New World College Dictionary, 4th Ed.
  8. acerbate: The Wordsmyth English Dictionary-Thesaurus
  9. acerbate: Infoplease Dictionary
  10. Acerbate, acerbate: Dictionary.com
  11. Acerbate: Online Plain Text English Dictionary
  12. acerbate: Webster's Revised Unabridged, 1913 Edition
  13. acerbate: Rhymezone
  14. Acerbate: AllWords.com Multi-Lingual Dictionary
  15. acerbate: Free Dictionary
  16. acerbate: The Phrontistery - A Dictionary of Obscure Words
  17. acerbate: Mnemonic Dictionary
  18. acerbate: Dictionary/thesaurus
  19. acerbate: Merriam-Webster.com

Business (1 matching dictionary)
  1. acerbate: Legal dictionary

Miscellaneous (1 matching dictionary)
  1. acerbate: A Word A Day

(Note: See acerbated as well.)

Definitions from Wiktionary (acerbate)

adjective:  (rare) Embittered; having a sour disposition or nature.
verb:  (transitive) To exasperate; to irritate.
verb:  (transitive) To make bitter or sour.

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