Usually means: Central nervous system depressant drug.
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We found 27 dictionaries that define the word GHB:

General (15 matching dictionaries)
  1. GHB: Merriam-Webster
  2. GHB: Oxford Learner's Dictionaries
  3. GHB: American Heritage Dictionary of the English Language
  4. GHB: Collins English Dictionary
  5. GHB: Vocabulary.com
  6. ghb: Wordnik
  7. GHB: Wiktionary
  8. GHB: Dictionary.com
  9. GHB (drug), GHB, Ghb: Wikipedia, the Free Encyclopedia
  10. Ghb: Rhymezone
  11. GHB: Stammtisch Beau Fleuve Acronyms
  12. ghb: FreeDictionary.org
  13. ghb: Mnemonic Dictionary
  14. GHB: TheFreeDictionary.com
  15. GHB: Merriam-Webster

Art (1 matching dictionary)
  1. Epicurus.com Coffee Glossary (No longer online)

Medicine (6 matching dictionaries)
  1. GHB: Merriam-Webster Medical Dictionary
  2. GHB: MedTerms.com Medical Dictionary
  3. GHB (gamma hydroxybutyrate): Merck Manuals
  4. Sleep Terms (No longer online)
  5. GHb: Medical dictionary
  6. GHB: Drug Medical Dictionary

Miscellaneous (2 matching dictionaries)
  1. GHB: Acronym Finder
  2. AbbreviationZ (No longer online)

Slang (2 matching dictionaries)
  1. GHB: Street Terms: Drugs and the Drug Trade
  2. G.H.B, ghb: Urban Dictionary

Sports (1 matching dictionary)
  1. GHB: Body Building

Definitions from Wiktionary (GHB)

noun:  (organic chemistry, biochemistry, pharmacology) Initialism of gamma-hydroxybutyrate, often used as a date rape drug. [(chemistry) Any salt or ester of gamma-hydroxybutyric acid, especially the sodium or potassium salts used as the drug "fantasy".]

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