Usually means: Stubborn person, often lacking sense.
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We found 4 dictionaries that define the word knothead:

General (2 matching dictionaries)
  1. knothead: Merriam-Webster
  2. knothead: Wiktionary

Medicine (1 matching dictionary)
  1. knothead: Medical dictionary

Slang (1 matching dictionary)
  1. knothead: Green’s Dictionary of Slang

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Definitions from Wiktionary (knothead)

▸ noun:  (informal) A stupid or stubborn person.

Similar:
knobber, snothead, knucklehead, knobhead, nuthead, bonehead, stupid-head, dumbhead, brickhead, bullet-head, more...

Opposite:
clever, intelligent, smart, astute, sharp



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Similar:
knobber, snothead, knucklehead, knobhead, nuthead, bonehead, stupid-head, dumbhead, brickhead, bullet-head, more...

Opposite:
clever, intelligent, smart, astute, sharp



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