Usually means: Leaving group in nucleophilic substitution.
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We found 4 dictionaries that define the word nucleofuge:

General (2 matching dictionaries)
  1. nucleofuge: Wiktionary
  2. Nucleofuge: Wikipedia, the Free Encyclopedia

Computing (1 matching dictionary)
  1. nucleofuge: Encyclopedia

Science (1 matching dictionary)
  1. nucleofuge: PHYSICAL ORGANIC CHEMISTRY

Definitions from Wiktionary (nucleofuge)

noun:  (chemistry) A leaving group that takes away a bonding electron pair with it

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