Usually means: Paralysis from contaminated alcohol consumption.
Definitions Related words Mentions
We found 7 dictionaries that define the word jake leg:

General (4 matching dictionaries)
  1. jake leg: Wiktionary
  2. jake leg: Dictionary.com
  3. Jake-leg: World Wide Words
  4. jake leg: Merriam-Webster

Medicine (1 matching dictionary)
  1. jake leg: Merriam-Webster Medical Dictionary

Slang (2 matching dictionaries)
  1. jake leg: Green’s Dictionary of Slang
  2. Jake Leg: Urban Dictionary

Definitions from Wiktionary (jake leg)

noun:  (US, slang, historical, 1930s and 40s) Paralysis of the feet and ankles caused by the consumption of TOCP (tri-ortho-cresyl phosphate) or methyl alcohol, found in adulterated moonshine or Jamaica ginger extract.

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