Usually means: Decline after reaching peak maturity.
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We found 12 dictionaries that define the word go to seed:

General (6 matching dictionaries)
  1. go to seed: Merriam-Webster
  2. go to seed: Oxford Learner's Dictionaries
  3. go to seed: Collins English Dictionary
  4. go to seed: Wiktionary
  5. go to seed: Dictionary.com
  6. go to seed: TheFreeDictionary.com

Business (1 matching dictionary)
  1. go to seed: Legal dictionary

Computing (1 matching dictionary)
  1. go to seed: Encyclopedia

Medicine (2 matching dictionaries)
  1. go to seed: Merriam-Webster Medical Dictionary
  2. go to seed: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. go to seed: Idioms

Slang (1 matching dictionary)
  1. go to seed: Urban Dictionary

Definitions from Wiktionary (go to seed)

verb:  (of a plant) To pass from flowering or ripening to the formation of seeds.
verb:  (figuratively, by extension) To deteriorate; to decline into an unkempt or debased condition.

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