Usually means: Biblical figure, son of Abraham.
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We found 33 dictionaries that define the word Isaac:

General (22 matching dictionaries)
  1. Isaac: Oxford Learner's Dictionaries
  2. Isaac: American Heritage Dictionary of the English Language
  3. Isaac: Collins English Dictionary
  4. Isaac: Vocabulary.com
  5. Isaac, isaac: Wordnik
  6. Isaac: Wiktionary
  7. Isaac: Webster's New World College Dictionary, 4th Ed.
  8. Isaac: The Wordsmyth English Dictionary-Thesaurus
  9. Isaac: Infoplease Dictionary
  10. Isaac: Dictionary.com
  11. Isaac: Online Etymology Dictionary
  12. ISAAC (cipher), ISAAC (comics), Isaac (Castlevania), Isaac (Golden Sun character), Isaac (Hollyn song), Isaac (Khazar), Isaac (Madonna song), Isaac (disambiguation), Isaac (name), Isaac (patriarch), Isaac: Wikipedia, the Free Encyclopedia
  13. Isaac: Rhymezone
  14. Isaac [Mendoza]: E Cobham Brewer, The Reader's Handbook
  15. Isaac: Dictionary of Phrase and Fable (1898)
  16. isaac: FreeDictionary.org
  17. isaac: Mnemonic Dictionary
  18. Isaac: TheFreeDictionary.com
  19. Isaac: Who2
  20. Isaac: Merriam-Webster
  21. isaac: Longman Dictionary of Contemporary English
  22. Isaac: Merriam-Webster

Art (1 matching dictionary)
  1. Natural Magick (No longer online)

Computing (1 matching dictionary)
  1. Isaac: Encyclopedia

Miscellaneous (3 matching dictionaries)
  1. baby names list (No longer online)
  2. ISAAC: Acronym Finder
  3. AbbreviationZ (No longer online)

Religion (4 matching dictionaries)
  1. Isaac: Easton Bible
  2. Isaac: Catholic Encyclopedia
  3. Isaac: Smith's Bible Dictionary
  4. Irivng Hexham's Concise Dictionary of Religion (No longer online)

Slang (2 matching dictionaries)
  1. Isaac (offensive): Racial Slur Database
  2. isaac: Green’s Dictionary of Slang

(Note: See isaacs as well.)

Definitions from Wiktionary (Isaac)

noun:  (biblical) The son of Abraham and Sarah, father of Esau and Jacob, from whom the Hebrew people trace their descent.
noun:  A male given name from Hebrew.
noun:  A surname originating as a patronymic.
noun:  Isaac Region, a local government area in central Queensland, Australia, named after the Isaac River.

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