Usually means: Loses control; behaves very erratically.
Definitions Related words Mentions History
We found 8 dictionaries that define the word spazzes:

General (6 matching dictionaries)
  1. spazzes: Merriam-Webster
  2. spazzes: Oxford Learner's Dictionaries
  3. spazzes: Wordnik
  4. spazzes: Wiktionary
  5. spazzes: Dictionary.com
  6. spazzes: TheFreeDictionary.com

Miscellaneous (1 matching dictionary)
  1. spazzes: Idioms

Slang (1 matching dictionary)
  1. spazzes: Urban Dictionary

(Note: See spaz as well.)

Definitions from Wiktionary (spaz)

noun:  An incompetent or physically uncoordinated person; a spazmo.
noun:  A hyperactive, erratically behaving person.
noun:  A tantrum or fit.
noun:  A person with spastic paralysis, spastic cerebral palsy or epilepsy
verb:  (slang, derogatory, offensive) To have a tantrum or fit.
verb:  (slang) To malfunction, go on the fritz.
▸ Also see spaz


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