Usually means: Inflict severe pain or torment.
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We found 23 dictionaries that define the word excruciate:

General (20 matching dictionaries)
  1. excruciate: Merriam-Webster
  2. excruciate: Oxford Learner's Dictionaries
  3. excruciate: American Heritage Dictionary of the English Language
  4. excruciate: Collins English Dictionary
  5. excruciate: Vocabulary.com
  6. excruciate: Wordnik
  7. excruciate: Wiktionary
  8. excruciate: Webster's New World College Dictionary, 4th Ed.
  9. excruciate: Infoplease Dictionary
  10. Excruciate, excruciate: Dictionary.com
  11. excruciate: Online Etymology Dictionary
  12. Excruciate: Online Plain Text English Dictionary
  13. excruciate: Webster's Revised Unabridged, 1913 Edition
  14. excruciate: Rhymezone
  15. Excruciate: AllWords.com Multi-Lingual Dictionary
  16. excruciate: Webster's 1828 Dictionary
  17. excruciate: FreeDictionary.org
  18. excruciate: Mnemonic Dictionary
  19. excruciate: TheFreeDictionary.com
  20. Excruciate: Dictionary of Phrase and Fable (1898)

Business (1 matching dictionary)
  1. excruciate: Legal dictionary

Computing (1 matching dictionary)
  1. excruciate: Encyclopedia

Medicine (1 matching dictionary)
  1. online medical dictionary (No longer online)

(Note: See excruciated as well.)

Definitions from Wiktionary (excruciate)

verb:  (transitive) To inflict intense pain or mental distress on (someone); to torture.
adjective:  (obsolete) Excruciated; tortured.

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