Usually means: Overwhelming astonishment, rendering one speechless.
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We found 23 dictionaries that define the word stupefaction:

General (20 matching dictionaries)
  1. stupefaction: Merriam-Webster
  2. stupefaction: Oxford Learner's Dictionaries
  3. stupefaction: American Heritage Dictionary of the English Language
  4. stupefaction: Collins English Dictionary
  5. stupefaction: Vocabulary.com
  6. Stupefaction, stupefaction: Wordnik
  7. stupefaction: Cambridge Advanced Learner's Dictionary
  8. stupefaction: Wiktionary
  9. stupefaction: Webster's New World College Dictionary, 4th Ed.
  10. stupefaction: The Wordsmyth English Dictionary-Thesaurus
  11. stupefaction: Infoplease Dictionary
  12. stupefaction: Dictionary.com
  13. Stupefaction: Online Plain Text English Dictionary
  14. stupefaction: Webster's Revised Unabridged, 1913 Edition
  15. stupefaction: Rhymezone
  16. Stupefaction: AllWords.com Multi-Lingual Dictionary
  17. stupefaction: Webster's 1828 Dictionary
  18. stupefaction: FreeDictionary.org
  19. stupefaction: Mnemonic Dictionary
  20. stupefaction: TheFreeDictionary.com

Business (1 matching dictionary)
  1. stupefaction: Legal dictionary

Computing (1 matching dictionary)
  1. stupefaction: Encyclopedia

Medicine (1 matching dictionary)
  1. stupefaction: Merriam-Webster Medical Dictionary

(Note: See stupefactions as well.)

Definitions from Wiktionary (stupefaction)

noun:  The state of extreme shock or astonishment.
noun:  A state of insensibility; stupor.

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