Might mean (unverified): Disease transmission from humans to animals.
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We found 2 dictionaries that define the word spillback:

General (2 matching dictionaries)
  1. spillback: The Word Spy
  2. spillback: Wiktionary

Definitions from Wiktionary (spillback)

noun:  The blockage of an intersection by traffic as a result of the traffic lights changing and preventing progress.
noun:  (epidemiology) The spread of an infectious pathogen from humans to non-human animals.

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