Usually means: Made a significant mistake; failed.
Definitions Related words Phrases Mentions
We found 18 dictionaries that define the word screwed up:

General (12 matching dictionaries)
  1. screwed up: Longman Dictionary of Contemporary English
  2. screwed up: Merriam-Webster
  3. screwed-up: Oxford Learner's Dictionaries
  4. screwed up: Collins English Dictionary
  5. screwed up: Vocabulary.com
  6. screwed-up: Wordnik
  7. screwed up: Cambridge Advanced Learner's Dictionary
  8. screwed up: Wiktionary
  9. Screwed Up: Wikipedia, the Free Encyclopedia
  10. Screwed Up, screwed-up: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. Screwed Up: Encyclopedia

Medicine (1 matching dictionary)
  1. Screwed Up: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. screwed up: Idioms

Slang (3 matching dictionaries)
  1. Screwed up: 1960's Slang
  2. screwed up: ESL Slang page
  3. screwed up: Urban Dictionary

Definitions from Wiktionary (screwed up)

adjective:  (of a piece of paper) Having been screwed into a ball.
adjective:  (idiomatic, vulgar) Morally reprehensible; clearly and grossly objectionable.
adjective:  (idiomatic, colloquial) Broken, damaged, inoperative or having only partial functioning, especially by inept handling.
adjective:  (idiomatic, colloquial) Having psychological problems; being mentally distraught or damaged.

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