Usually means: Behave uncontrollably and disruptively wild.
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We found 9 dictionaries that define the word run amuck:

General (6 matching dictionaries)
  1. run amuck: Merriam-Webster
  2. run amuck: Wiktionary
  3. run amuck: Dictionary.com
  4. Run Amuck: Dictionary of Phrase and Fable (1898)
  5. Run amuck: TheFreeDictionary.com
  6. Run amuck: Phrase Finder

Computing (1 matching dictionary)
  1. Run amuck: Encyclopedia

Medicine (1 matching dictionary)
  1. Run amuck: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. Run amuck: Idioms

Definitions from Wiktionary (Run amuck)

verb:  Alternative form of run amok [(idiomatic) To go on a rampage; to be in an uncontrollable rage.]

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