Usually means: Open reading frames in DNA.
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We found 7 dictionaries that define the word orfs:

General (4 matching dictionaries)
  1. orfs: Collins English Dictionary
  2. ORFs, orfs: Wiktionary
  3. ORFS: Dictionary.com
  4. ORFS: Wikipedia, the Free Encyclopedia

Medicine (1 matching dictionary)
  1. orfs: Merriam-Webster Medical Dictionary

Miscellaneous (2 matching dictionaries)
  1. ORFS: Acronym Finder
  2. AbbreviationZ (No longer online)

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