Usually means: Synthetic fat substitute, calorie-free.
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We found 15 dictionaries that define the word olestra:

General (11 matching dictionaries)
  1. olestra: Merriam-Webster
  2. olestra: Oxford Learner's Dictionaries
  3. olestra: American Heritage Dictionary of the English Language
  4. Olestra: Collins English Dictionary
  5. Olestra, olestra: Wordnik
  6. olestra: Wiktionary
  7. olestra: Dictionary.com
  8. olestra: Cambridge Essential American English Dictionary
  9. Olestra: Wikipedia, the Free Encyclopedia
  10. olestra: Stammtisch Beau Fleuve Acronyms
  11. olestra: TheFreeDictionary.com

Medicine (2 matching dictionaries)
  1. olestra: Merriam-Webster Medical Dictionary
  2. Olestra: Medical dictionary

Slang (1 matching dictionary)
  1. olestra: Urban Dictionary

Sports (1 matching dictionary)
  1. Olestra: Body Building

Definitions from Wiktionary (olestra)

noun:  A fat substitute (a glyceride of sucrose) that cannot be easily digested and therefore adds no fat, calories, or cholesterol to food products; also used as an industrial lubricant.

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