Usually means: Wife, often used informally, colloquially.
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We found 22 dictionaries that define the word missis:

General (21 matching dictionaries)
  1. missis: Longman Dictionary of Contemporary English
  2. missis: Merriam-Webster
  3. missis: Oxford Learner's Dictionaries
  4. missis: American Heritage Dictionary of the English Language
  5. missis: Collins English Dictionary
  6. missis: Vocabulary.com
  7. Missis, missis: Wordnik
  8. missis: Wiktionary
  9. missis: Webster's New World College Dictionary, 4th Ed.
  10. missis: Infoplease Dictionary
  11. Missis, missis: Dictionary.com
  12. Missis: Wikipedia, the Free Encyclopedia
  13. Missis: Online Plain Text English Dictionary
  14. missis: Webster's Revised Unabridged, 1913 Edition
  15. missis: Rhymezone
  16. Missis: AllWords.com Multi-Lingual Dictionary
  17. missis: FreeDictionary.org
  18. missis: Mnemonic Dictionary
  19. missis: TheFreeDictionary.com

Slang (1 matching dictionary)
  1. missis: Green’s Dictionary of Slang

(Note: See mississ as well.)

Definitions from Wiktionary (
)
American English Definition British English Definition
noun:  (US, historical, colloquial) Pronunciation spelling of missus, representing African-American Vernacular English. [(colloquial) Wife or girlfriend.]
noun:  (UK, colloquial) Alternative spelling or pronunciation spelling of missus. [(colloquial) Wife or girlfriend.]

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