Definitions from Wiktionary ( )

▸ verb:  (transitive) To move, arrange or operate something using the hands
▸ verb:  (transitive) To influence, manage, direct, control or tamper with something
▸ verb:  (transitive, medicine) To handle and move a body part, either as an examination or for a therapeutic purpose
▸ verb:  (transitive) To influence or control someone in order to achieve a specific purpose, especially one that is unknown to the one being manipulated and beneficial to the manipulator; to use
▸ verb:  (intransitive, dated) To use the hands, especially in scientific experiments.

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