Usually means: Lose focus or become irrational.
Definitions Related words Mentions
We found 9 dictionaries that define the word lose the plot:

General (6 matching dictionaries)
  1. lose the plot: Merriam-Webster
  2. lose the plot: Oxford Learner's Dictionaries
  3. lose the plot: Collins English Dictionary
  4. lose the plot: Cambridge Advanced Learner's Dictionary
  5. lose the plot: Wiktionary

Miscellaneous (1 matching dictionary)
  1. lose the plot: Idioms

Slang (2 matching dictionaries)
  1. lose the plot: English slang and colloquialisms used in the United Kingdom
  2. Lose the plot: Urban Dictionary

Definitions from Wiktionary (lose the plot)

verb:  (UK, idiomatic, colloquial) To cease to behave in a consistent or rational manner.
verb:  (UK, idiomatic, colloquial) To lose sight of an important objective or principle; to act contrarily to one's own interests through concentrating on relatively unimportant matters.
verb:  Used other than figuratively or idiomatically: see lose, plot.

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