Usually means: Brain smoothness due to malformations.
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We found 13 dictionaries that define the word lissencephaly:

General (5 matching dictionaries)
  1. lissencephaly: Merriam-Webster
  2. lissencephaly: Wordnik
  3. lissencephaly: Wiktionary
  4. lissencephaly: Dictionary.com
  5. Lissencephaly: Wikipedia, the Free Encyclopedia

Medicine (8 matching dictionaries)
  1. lissencephaly: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. Lissencephaly: MedTerms.com Medical Dictionary
  4. online medical dictionary (No longer online)
  5. Specific Diseases/Disorders (No longer online)
  6. Disorder Index (No longer online)
  7. lissencephaly: Medical dictionary
  8. Lissencephaly: Drug Medical Dictionary

Definitions from Wiktionary (lissencephaly)

noun:  (anatomy, neurology) The condition of having a smooth appearance on the surface of the brain.
noun:  (medicine) An abnormality of brain development marked by the presence of a smooth cerebral cortex with few or no convolutions; frequently associated with severe developmental disability.

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