Usually means: Blocked pore causing skin blemish.
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We found 29 dictionaries that define the word comedo:

General (19 matching dictionaries)
  1. comedo: Merriam-Webster
  2. comedo: Oxford Learner's Dictionaries
  3. comedo: American Heritage Dictionary of the English Language
  4. comedo: Collins English Dictionary
  5. comedo: Vocabulary.com
  6. comedo: Wordnik
  7. comedo: Wiktionary
  8. comedo: Webster's New World College Dictionary, 4th Ed.
  9. comedo: The Wordsmyth English Dictionary-Thesaurus
  10. comedo: Infoplease Dictionary
  11. comedo: Dictionary.com
  12. Comedo: Wikipedia, the Free Encyclopedia
  13. Comedo: Online Plain Text English Dictionary
  14. comedo: Webster's Revised Unabridged, 1913 Edition
  15. comedo: Rhymezone
  16. Comedo: AllWords.com Multi-Lingual Dictionary
  17. comedo: FreeDictionary.org
  18. comedo: Mnemonic Dictionary
  19. comedo: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. comedo: Encyclopedia

Medicine (7 matching dictionaries)
  1. comedo: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. Comedo: MedTerms.com Medical Dictionary
  4. Breast Cancer Talking Dictionary (No longer online)
  5. online medical dictionary (No longer online)
  6. comedo: Medical dictionary
  7. Comedo: Drug Medical Dictionary

Slang (1 matching dictionary)
  1. comedo: Urban Dictionary

Tech (1 matching dictionary)
  1. Washington State Definitions and Abbreviations of Vetrinary Terms (No longer online)

(Note: See comedones as well.)

Definitions from Wiktionary (comedo)

noun:  (medicine) A clogged hair follicle in the skin, formed when keratin combines with oil to block the follicle; it can manifest as an open comedo (blackhead) or a closed comedo (whitehead).

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